【摘要】 [目的]探讨乙型肝炎肝硬化患者的中医证型与血清神经肽(NPY)水平的相关性。[方法]比较代偿期与失代偿期患者的血清NPY值;规范医生对乙型肝炎肝硬化患者的辨证结果,分别选取代偿期与失代偿期中出现频次高的前5个证候并比较不同证候间的血清NPY值。运用SPSS18.0统计软件包进行统计分析。[结果]代偿期和失代偿期乙型肝炎肝硬化患者血清NPY水平的分别为119.135 0、72.860 0,且差异有统计学意义(P<0.05)。血清NPY水平在代偿期各证型之间差异有统计学意义,且肝郁脾虚组>气滞血瘀组>湿热蕴结组>肝肾阴虚组>肝气郁结组;在失代偿期五组之间差异无统计学意义。[结论]血清NPY水平与疾病的进展有关,与代偿期乙型肝炎肝硬化的中医证型有关。更多还原

【Abstract】 [Objective] To investigate the hepatitis B patients with cirrhosis of traditional Chinese medicine(TCM) syndrome and the correlation of serum NPY levels. [Methods] Compare compensation period and decompensation period in patients with serum NPY value.Doctor specification of syndrome differentiation in patients with hepatitis B cirrhosis of the liver as a result, the compensation period and decompensation period appear respectively selected high frequency of the first five syndromes and compare the value of serum NPY between different syndrome. Using the SPSS18.0 statistical software package for statistical analysis. [Results] Compensation period and decompensation period NPY levels in the serum of patients with hepatitis B cirrhosis of the liver were 119.135 0, 72.910 0, and the difference was statistically significant(P < 0.05). Serum NPY level in compensatory phase difference was statistically significant among different syndrome types, and stagnation of liver Qi and spleen deficiency group > Qi and blood stasis group > damp and hot accumulate knot > liver-kidney Yin deficiency group > move within group. In decompensated period there was no statistically significant difference between groups of five. [Conclusion] Serum NPY levels associated with disease progression, and the compensatory phase of hepatitis B cirrhosis related to the TCM syndrome type.更多还原