Objective To investigate the effects of Tangshen Formula on liver oxidative stress in diabetic rats, andtheir mechanisms thereof.Methods Rat model of type 2 diabetes mellitus and nonalcoholic fatty liver disease was estab-lished by intraperitoneally injecting small dose of chain urea with cephalosporins(STZ) and feeding high fat fodder.Themodel rats were randomly divided into control group, model group, Tangshen Formula group and metformin group.The se-rum levels of alanine aminotransferase(ALT), aspartate ...