【摘要】 目的:探讨首发精神分裂症患者的学习能力和执行能力与其精神状态的相关性。方法:选取本院2014年1月至10月收治的35例首发精神分裂症患者和35例正常健康的人员作为研究对象,即相应为实验组和对照组。对两组受试者进行威斯康星卡片分类测评(WSCT)、持续操作测评(CPT)、可重复使用的成套神经及心理状态的测评工具(RBANS)、Stroop色词测评及阳性与阴性症状量表(PANSS)评定,评定其学习能力、执行能力及精神状态,并分析其相关性。结果:与对照组相比,实验组除Stroop色词测评中的卡片A(字)、B(色)、C(字色)的错误数差异无统计学意义(P>0.05)外,其余各项心理测评指标均明显降低(P<0.05)。多项心理测评成绩如WSCT测评中的随机错误数、CPT测评中的正确反应时、RBANS测评的瞬时记忆分和总分、Stroop色词测验评中的字义干扰及颜色干扰时,均与PANSS的精神状态评分呈相关性(P<0.05)。结论:首发精神分裂症患者的注意力、执行力、记忆力及言语能力均发生了障碍,其学习能力和执行能力与其精神状态均呈相关性。更多还原

【Abstract】 Objective: To explore the correlation between cognitive function and executive function and psychiatric symptoms in patients with schizophrenia. Methods: Thirty-five patients with schizophrenia from Jan,2014 to Oct,2014 in the hospital and thirty-five healthy people were chosen as research cases. They were divided into experimental group and control group. They were evaluated by neuropsychological test,such as Wisconsin card sorting test( WSCT),continuous performance test( CPT),repeatable battery for the assessment of neuropsychological status( RBANS) and Stroop color-word test and the positive and negative syndrome scale( PANSS) in schizophrenic patients to test the cognitive function and executive function and psychiatric symptoms in patients with schizophrenia,and the correlation were analyzed between them. Results: Compared with the control group,the scores of neuropsychological test in schizophrenic patients except the A,B,C wrong doing of Stroop color-word test,were lower significantly( P < 0. 05). The random wrong doing in WSCT,the correct time in CPT,immediate memory score and total score in RBANS,word interference time and color interference time in Stroop color-word test were correlated with scores in PANSS significantly( P < 0. 05). Conclusion: The attention,memory,verbal function and executive performance were impaired in patients with schizophrenia,and the cognitive function and executive function were correlated with the psychiatric symptoms significantly.更多还原