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通络醒脑方联合西药治疗脑梗死急性期随机平行对照研究

Tongluo Xingnao Soup combined Western Medicine Randomized Controlled Study of Acute Cerebral Infarction

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【作者】 李晓

【Author】 LI Xiao;Beiliu City Hospital Encephalopathy;

【机构】 广西北流市中医院脑病科

【摘要】 [目的]观察通络醒脑方联合西药治疗脑梗死急性期疗效。[方法]使用随机平行对照方法,将68例住院患者按抛硬币法简单随机分为两组。对照组34例抗血小板聚集、抗凝、调脂、调控血压及血糖,脑神经保护及对症支持治疗、并发症治疗等。治疗组34例通络醒脑方(天麻12g,半夏、胆南星、地龙各10g,全蝎5g,石菖蒲20g,川芎12g,鸡血藤30g,水蛭、大黄各10g,丹参12g,甘草5g),1剂/d,水煎200m L,早晚分服;西药治疗同对照组。连续治疗14d为1疗程。观测临床症状、NIHSS评分、不良反应。治疗1疗程,判定疗效。[结果]治疗组临床控制8例,显效19例,有效4例,无效3例,总有效率91.18%。对照组临床控制5例,显效6例,有效13例,无效10例,总有效率70.59%。治疗组疗效优于对照组(P<0.05)。NIHSS评分两组均有改善(P<0.01),治疗组改善优于对照组(P<0.01)。[结论]通络醒脑方联合西药治疗脑梗死急性期疗效满意,无严重不良反应,值得推广。

【Abstract】 [Objective]To observe the Tongluo Xingnao soup combined with western medicine on acute cerebral infarction.[Methods]randomized,parallel controlled method,68 patients were hospitalized method is simple coin toss randomized into two groups.The control group of 34 patients anti-platelet aggregation,coagulatio n,lipid,blood pressure and blood sugar regulation,neuroprotective and symptomatic and supportive treatment,com plications,treatment.Treatment group,34 patients Tongluo refreshing party(Tianma 12 g,Banxia,Dannanxing,Dilong 10 g,Quanxie 5g,Shichangpu 20 g,Chuanxiong 12 g,Jixuetng 30 g,Shuizhi,Dahuang 10 g,Danshen 12 g,Gancao 5g), 1/d,decoction 200 m L,morning and evening hours;western medicine with the control group.14 d for a course of continuous treatment.Observation of clinical symptoms,NIHSS score,adverse reactions.One course of treatment,to determine efficacy.[Results]8 cases control treatment group,19 cases were markedly effective in 4 cases,3 cases,the total efficiency of 91.18%.Clinical control group 5 cases,effective in 6 cases,effective in 13 cases,10 cases,the total efficiency of 70.59%.Treatment group than the control group(P<0.05).NIHSS scores improved in both groups(P<0.01),the treatment group than the control group improved(P<0.01).[Conclusion]Tongluo Xingnao soup combined with western medicine treatment of acute cerebral infarction results were satisfactory,no side effects,worthy of promotion.

  • 【文献出处】 实用中医内科杂志 ,Journal of Practical Traditional Chinese Internal Medicine , 编辑部邮箱 ,2015年08期
  • 【分类号】R743.3
  • 【下载频次】50
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