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平喘汤联合孟鲁斯特钠治疗支气管哮喘随机平行对照研究

Montelukast Sodium Soups and Asthma Combined Treatment of Bronchial Asthma Randomized Parallel Group Study

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【作者】 莫健平

【Author】 MO Jianping;City of Guangdong Province Hospital of Lung Disease Branch;

【机构】 广东省高州市中医院肺病科

【摘要】 [目的]观察平喘汤联合孟鲁斯特钠治疗支气管哮喘疗效。[方法]使用随机平行对照方法,将142例住院患者按病志号抽签法简单随机分为两组。对照组71例孟鲁斯特钠,10mg/次,1次/d,睡前口服。治疗组71例平喘汤(麻黄6g,杏仁10g,川芎3g,黄芩5g,白芥子6g,甘草2g;固本平喘加黄芩、地龙;宣肺平喘加葶苈子、苏子、半夏),1剂/d,水煎200m L,早晚口服;西药治疗同对照组。连续治疗30d为1疗程。观测临床症状、哮喘、不良反应。治疗1疗程,判定疗效。[结果]治疗组痊愈19例,显效24例,有效17例,无效11例,总有效率84.51%。对照组痊愈17例,显效23例,有效15例,无效18例,总有效率75.34%。临床疗效两组无明显差异(P>0.05)。生活质量评分两组均有改善(P<0.05),治疗组改善优于对照组(P<0.01)。[结论]平喘汤联合孟鲁斯特钠治疗支气管哮喘,疗效满意,无严重不良反应,值得推广。

【Abstract】 [Objective]To observe the therapeutic effect of Pingchuan decoction combined with montelukast sodium in the treatment of bronchial asthma [Methods] Randomized parallel-group method using the 142 cases of hospitalized patients by disease Zhi No. balloting method is simple and randomized into two groups. 71 cases in the control group Montelukast sodium, 10 mg / times, 1 times / d, orally at bedtime. Treated 71 cases of asthma soup(Mahuang 6g, Xingren 10 g, Chuanxiong 3g, Huangqin 5g, Baijiezi 6g, Gancao2g; consolidate asthma plus Huangqin,Dilong; Xuanfei asthma plus Tinglizi, Suzi, Banxia), a / d, decoction 200 m L, sooner or later oral; Western medicine with the control group. 30 d for a course of continuous treatment. Observation of clinical symptoms, asthma, adverse reactions. A course of treatment to determine efficacy. [Results] The cure 19 cases, 24 cases markedly effective in 17 cases, 11 cases, the total efficiency of 84.51%. Cured 17 cases in the control group, 23 cases markedly effective in 15 cases, 18 cases, the total efficiency of 75.34%. The clinical efficacy of the two groups had no significant difference(P>0.05). Quality of life scores of the two groups were improved(P<0.05), the treatment group was better than the control group(P<0.01)[Conclusion] Asthma soup joint Montelukast sodium Montelukast sodium in the treatment of bronchial asthma in effect no big difference.

  • 【文献出处】 实用中医内科杂志 ,Journal of Practical Traditional Chinese Internal Medicine , 编辑部邮箱 ,2015年04期
  • 【分类号】R562.25
  • 【被引频次】1
  • 【下载频次】42
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