This paper summarizes the rules of hydrocarbon accumulation and their controlling factors,and predicts some favorable exploration targets based on the integrated analysis of the basic geological features and distribution of discovered oil and gas fields in the Amu Darya Basin. In map view,the distribution of oil and gas fields is controlled mainly by source rocks,structures and lithology. The phenomenon of differential accumulation of oil and gas is also obvious. There are sub-salt and supra-salt petroleum-...