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肾上腺皮质嗜酸细胞腺瘤的MSCT表现与病理分析
CT diagnosis and pathological analysis of adrenocortical oncocytoma
【摘要】 目的 探讨肾上腺皮质嗜酸细胞腺瘤(ACO)的CT表现,以提高对该病的认识和诊断水平。方法 回顾分析9例经手术、病理证实的ACO的CT特征,并与病理结果进行对照。结果 9例中5例位于左侧,4例位于右侧,病变边界清楚,呈圆形或椭圆形。其中实性病变3例,肿瘤直径<3 cm,密度均匀,增强后病灶中度持续强化;囊实性病变6例,肿瘤直径>3 cm, CT表现为囊性与实性成分相互掺杂,呈多囊样改变,增强后实性部分明显强化,囊性部分未见强化;其中4例病灶实性成分呈片状、絮状强化,1例呈岛屿状强化;3例病灶中央见网格样分隔,1例见星芒状改变。镜下肿瘤由胞质内充满嗜酸颗粒的嗜酸细胞组成,部分病灶内见坏死及纤维组织分隔,细胞无病理性核分裂象。结论 ACO的CT表现具有一定特征性,但特异性不高,最后诊断常需依靠病理证实。
【Abstract】 Objective To explore the computed tomography(CT) manifestations of adrenocortical oncocytoma(ACO) for better understanding the disease and improving its diagnosis accuracy.Methods The CT manifestations of 9 cases with adrenocortical oncocytomas confirmed by surgery were retrospectively reviewed and compared with pathological results.Results Five of cases were located in left side while 4 cases were in right side.Well defined and round or oval border could be found in all the cases.Of all the cases,3 cases were solid lesions with equal density,<3 cm in diameter,and mild consistent intensification after enhancement.Cystic lesion was detectd in 6 cases with> 3 cm in diameter.The mixed cystic and solid components with polycystic changes could be found on CT image,and remarkable intensification on solid lesion while no intensification on cystic lesion after the enhancement.Moreover,patchy or cotton-like shape could be found on solid lesion in 4 cases and 1 case with island like intensification;reticular pattern could be found in the central of lesion in 3 cases and 1 case with stellate shape.Pathological observation showed that the oncotytomas were comprised of cells with abundant eosinophilic cytoplasm and necrotic and fibrous capsule without pathological mitosis could be found in some of lesion.Conclusion The characteristic CT features of adrenocortical oncotytoma has a worse specificity,its diagnosis was dependent on pathologic examination.
- 【文献出处】 实用放射学杂志 ,Journal of Practical Radiology , 编辑部邮箱 ,2015年10期
- 【分类号】R730.44;R736.6