【摘要】 目的 分析肝脏原发性神经内分泌癌（PHNEC）的影像学表现，旨在提高对该肿瘤的认识。方法 回顾性分析经病理证实的5例PHNEC的影像学资料。术前4例行CT平扫及增强扫描，1例行MRI平扫及增强扫描。结果 4例行CT检查，单发2例，多发2例，肿瘤最大径5.5～10 cm。平扫表现为肝内低密度占位，病灶中央可见不规则更低密度区，边界尚清楚，动态增强后动脉期病灶实质部分明显不均匀强化，门脉期及延迟期仍有强化，强化的范围较动脉期增大，中央低密度区不强化。1例行MRI检查，为单发病灶，最大径5.0 cm,位于肝右后叶，T₁WI为低信号，T₂WI、DWI均为高信号，周边可见小圆形囊性信号，强化方式呈持续性轻～中度强化。肿块周围肝内血管受压移位，但无癌栓形成，腹腔及后腹膜均未见明显肿大淋巴结。结论 CT和MRI能基本反映PHNEC的特征，在该病的诊断与鉴别诊断中有一定价值。更多还原

【Abstract】 Objective To investigate the imaging features of primary hepatic neuroendocrine carcinoma.Methods The imaging features of primary hepatic neuroendocrine carcinoma confirmed by pathology in 5 patients were reviewed retrospectively. Among the patients, plain and contrast enhanced CT in 4 and plain and contrast enhanced MRI in 1 were performed.Results CT showed a single lesion in 2 patients and multiple lesions in other 2 with the maximum diameter of 5.5 cm-10 cm. On plain CT,all lesions were hypodensity with clear boundary and lower area in the center. The enhanced CT showed the lesions with obvious enhancement in arterial phase and gradually increasing enhanced area in portal vein and delayed phases but without enhancement in the lesion center. MRI showed the only one lesion in 1 patient with heterogenerous hypointensity on T₁WI,hyperintersity on T₂WI and DWI,and with mild to moderate delayed enhancement. The maximum diameter of the lesion was 5.0 cm, accompanied by a small round cystic structure at the periphery. The compression and displacement of peripheral blood vessels by the lesion without thrombus, and no lymphadenopathy were also identified.Conclusion CT and MRI may show the imaging characteristics of the primary hepatic neuroendocrine carcinoma, which is helpful for the diagnosis of the tumor.更多还原