【摘要】 目的 探讨原发性胆汁性肝硬化（PBC）的磁共振成像（MRI）表现,提高该病的诊断水平。方法 回顾分析5例经病理或临床确诊的PBC的MRI表现特点,并作文献复习。本组5例PBC患者行MRI常规序列T₁WI、T₂ WI、DWI等序列扫描及MRI胰胆管成像检查。结果 本组3例患者出现肝内门静脉及其分支的管壁光滑、增厚。3例患者肝内门静脉及其分支周围出现“月晕征”。4例患者出现肝内2～3级胆管显示不清,3例患者肝内外胆管壁光滑,管腔变小。5例患者门静脉周围可见条片状长T₂信号及腹腔内肿大的淋巴结。3例患者出现腹水和胆囊体积变小。4例患者脾脏体积增大。结论 肝内门静脉及其分支周围形成的“月晕征”、肝外门静脉周围环绕异常的长T₂信号、肝内2～3级胆管显示不清和胆管管腔变小和脾脏体积增大是PBC主要的MRI表现。更多还原

【Abstract】 Objective To discuss the MRI manifestations of primary biliary cirrhosis in order to improve the diagnosis.Methods The MRI manifestations of primary biliary cirrhosis proved by pathology and clinical diagnosis in 5 patients were analyzed retrospectively.The patients underwent plain T₁WI,T₂WI,DWI（b=0,800 s/mm²） and magnetic resonance cholangiopancreatography.Results MRI showed the thickening and smooth portal vein wall with hyperintensity on T₂WI in 3 patients.The "periportal halo" sign with hypointensity on T₁WI and hyperintensity on T₂WI was observed around portal venous branches in 3 patients.Unclear 2-3 grades of intrahepatic bile ducts were found in 4,and narrow lumens of intrahepatic and extrahepatic bile ducts were also found in 3.Periportal hyperintensity on T₂WI and DWI and enlarged lymph nodes in abdomen were also revealed in 5.Mild ascites and shrinking gallbladder volume were showed in 3.Splenomegaly was showed in 4.Conclusion MR manifestations of periportal hyperintensity on T₂WI, "periportal halo" sign,splenomegaly,unclear 2-3 grades of intrahepatic bile duct and narrow lumen of intrahepatic and extrahepatic bile duct may paly an important role in diagnosis of primary biliary cirrhosis.更多还原