【摘要】 目的 探讨双源CT(DSCT)评估主动脉瓣返流(AR)的可行性及准确性。方法 78例同时行DSCT冠状动脉成像及经胸心脏超声(TTE)检查,其中AR患者38例,正常者40例做对照。DSCT面积法测量舒张期最大返流面积(ROA),以TTE半定量评估返流程度为对照。结果 DSCT发现37例AR,假阳性2例,假阴性3例(敏感性92%,特异性95%,阳性预测值94%,阴性预测值93%)。DSCT所测ROA值(0.32 cm~2±0.44 cm~2)与TTE返流程度分级间具有明显相关性(r=0.85,P<0.01)。通过受试者工作特征曲线分析表明,采用ROA 0.08 cm~2、0.58 cm~2分别作为区分返流程度分级的指标,其准确性较高。结论 DSCT采用面积法测量ROA可对AR进行准确定量评估。更多还原

【Abstract】 Objective To explore the feasibility and accuracy of dual-source CT(DSCT) in evaluating aortic regurgitation(AR).Methods Among 78 patients who underwent both DSCT and TTE,38 patients were diagnosed as AR and 40 without AR served as controls.Maximum regurgitant orifice area(ROA) in diastole was planimetrically measured with DSCT,and measurements were compared with semiquantitative classification of TTE.Results DSCT correctly identified 37 patients with AR.Compared with TTE,two patients were false positive and three patients were false negative findings by DSCT(sensitivity 92%,specificity 95%,positive predictive value 94%,and negative predictive value 93%).ROA measured by DSCT(0.32 cm~2+0.44 cm~2) was significantly correlated with TTE classification(r=0.85,P<0.01).With receiver operating characteristic curve analysis,discrimination between degrees of AR with DSCT was high accurate when using cutoff ROAs of 0.08 cm~2 and 0.58 cm~2.Conclusion Planimetric measurement of ROA with DSCT is accurate for the quantitative evaluation of AR.更多还原