【摘要】 目的 探讨慢性阻塞性肺疾病(COPD)所致的支气管动脉(BA)改变及其CTA表现特征。方法 将43例COPD病例依据慢性阻塞性肺疾病全球倡议(GOLD)分为4组(GOLD 1级组，GOLD 2级组，GOLD 3级组，GOLD 4级组),并随机选取同期来本科就诊的查体健康者10例作为对照组。将所有病例的胸部CT增强扫描的原始数据0.625 mm薄层重建后，对BA三维重建。统计各组BA的主干及分支计数，评价其形态变化情况，并比较各组间差异。结果 与对照组相比，GOLD 2～4级的BA主干计数增高(P≤0.05),GOLD 3～4级BA分支计数增高(P≤0.05);与GOLD 1级组相比，GOLD 4级BA主干计数增高(P≤0.05),GOLD 3～4级BA分支计数增高(P≤0.05);其余各组间无统计学差异。与对照组、GOLD 1级组相比，GOLD 3～4级的BA形态迂曲，组间差异具有统计学意义(P≤0.05)。结论 COPD患者BA形态迂曲，CTA检查显示率高，这种变化在中度或极重度COPD患者(GOLD 3～4级)中显著。与其他肺部疾病相比，COPD产生的BA改变具有一定的特征性。更多还原

【Abstract】 Objective To determine the change of bronchial artery(BA) caused by COPD and its character on CTA.Methods 43 patients with COPD were collected and divided into 4 groups according to the Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease(GOLD). 10 healthy persons were collected as control group. Data of enhanced chest CT from all cases were collected. In combination with 0.625 mm thin slice reconstruction, MPR, MIP and VR, counted the number of BA(main trunk and branch), analysised characteristic change of BA in patient with COPD.Results Compared with control group, quantity of main trunk of BA was increased in GOLD 2-4(P≤0.05), and quantity of branch BA was increased in GOLD 3-4(P≤0.05).Compared with control group and GOLD 1,morphology of BA was significantly tortuose in GOLD 3-4(P≤0.05).Conclusion Tortuosity BA could be observed in patient with COPD. Increased quantity of BA is showed on enhenced CT and 3D reconstrucion CT image with the exacerbation of the disease. Character change is significant in those serious and very serious COPD patients(GOLD 3-4).Feature of BA with COPD is different with other diseases.更多还原