【摘要】 目的 探讨颅内脱髓鞘假瘤(DPTs)的MRI影像表现。方法 回顾性分析10例经临床最终诊断为DPTs的MRI影像资料，所有患者均行MRI平扫，其中9例行增强扫描，7例行扩散加权成像(DWI),2例行单体素短回波~1HMRS。结果 其中8例患者病灶周围伴有轻～中度水肿，5例表现为多发病灶，3例表现为单发结节灶，2例表现为单发片状病灶。增强扫描中4例为开环形强化，3例为环形强化，1例结节状强化，1例斑片状强化。病灶在DWI上均表现为高信号，~1HMRS示2例均有NAA峰不同程度降低，Cho峰、Lac和Lip峰升高，1例谷氨酸/谷氨酰胺复合物(Glx峰)明显升高。结论 DPTs在MRI影像上有一定特点，特征性表现为开环形强化，结合DWI及~1HMRS技术有助于DPTs和其他病变鉴别。更多还原

【Abstract】 Objective To characterize the MRI features of demyelinating pseudotumors(DPTs).Methods MR data of 10 cases clinically proved with DPTs were retrospectively analyzed. All cases were underwent MRI scan, 9 of 10 cases were performed with enhanced MRI,7 cases were underwent diffusion weight imaging(DWI),2 cases were performed with single voxel short echo ~1H-MRS.Results 8 cases showed lesions with mild to moderate edema, 5 cases showed multiple lesions, 3 cases were solitary nodular lesions, 2 cases were solitary flaky lesions.On enhanced MRI,4 cases presented with open ring like enhancement, 3 cases presented ring like enhancement, 1 case with nodular enhancement, and 1 case showed patchy enhancement. All lesions showed high signal in DWI. In ~1H-MRS, 2 cases demonstrated varying decrease in peaks heights of Nacetylaspartate(NAA),elevation of the choline(Cho), the lactate(Lac) and lipids(1ip).1 case demonstrated evident elevation in peaks height of glutamate/glutamine(Glx).Conclusion DPTs has some characteristics on MRI, especially as open ring like enhancement. It is helpful to identified DPTs from other lesions when together with DWI and ~1H-MRS.更多还原