【摘要】 目的探讨胸腔积液肿瘤标志物联合检测在临床上的应用价值。方法选择42例恶性胸腔积液患者为试验组,同时选择同期检查的42例良性胸腔积液患者作为对照组,分别采用免疫化学发光法来对这些患者的CA125和CA153以及CA199、CEA水平进行联合检测,并对这些肿瘤标志物的水平与单独检测结果进行比较和分析。结果试验组患者的肿瘤标志物CA125和CA153以及CA199、CEA含量均明显高于对照组(P<0.05)。此外,试验组单项肿瘤标志物的检测敏感度要明显低于肿瘤标志物联合检测(P<0.05)。试验组中CEA、CA199、CA153的阳性率明显高于对照组(P<0.01);而2组CA125阳性率比较,P>0.05。结论临床上,采用胸腔积液肿瘤标志物联合检测,能够有效地提高临床诊断敏感度,为患者合理地选择治疗方案以及及早、及时治疗,避免患者病情恶化。更多还原

【Abstract】 Objective To explore the clinical value of combined detection of pleural effusions tumor markers. Methods42 cases of malignant pleural effusion patients was the experimental group,42 cases of benign pleural effusion patients was the control group,the immune chemiluminescence method was used in combined detection of CA125,CA153,CA199,CEA levels,and the levels of tumor markers and single detection were compared. Results CA153,CA199 and CA125,CEA levels in the experimental group were significantly higher than those of the control group( P < 0. 05). In addition,detection sensitivity of single tumor markers was significantly lower than of combined tumor marker( P < 0. 05). Positive rates of CEA,CA199,CA153 in the experimental group was obviously higher than those of the control group( P < 0. 01); And CA125 positive rate of the 2 groups had no significant difference( P > 0. 05). Conclusion Clinically,joint pleural effusions tumor markers detection can effectively improve the clinical diagnostic sensitivity,timely and reasonable treatment can avoid deterioration.更多还原