Objective:To investigate the changes of serum hypoxia inducible factor-1α(HIF-1α) and vascular endothelial growth factor( VEGF) before and after chemotherapy in patients with non-small cell lung cancer(NSCLC).Methods:The serum levels of HIF-1α and VEGF in 22 cases with advanced NSCLC were measured by enzyme linked immunossorbent assay( ELISA) before and after chemotherapy.Results:The total clinical treatment efficacy of patients was 27%.The serum levels of HIF-1α and VEGF were elevated after chemotherapy,bu...
【基金】
南京医科大学科技发展基金重点项目(编号:2010njmuz53)
【更新日期】
2015-04-02
【分类号】
R734.2
【正文快照】
Modern Oncology 2015,23(06):0791-0794【修回日期】2014-09-13因子-1α(hypoxia inducible factor-1,HIF-1α)、血管内皮生长因子(vascular endothelial growth factor,VEGF)与化疗疗效之间的关系。方法:选择本院收治的22例NSCLC患者,采用酶联免疫吸附试验法(enzyme linkedim