【摘要】 目的:研究分析早期介入微弹簧圈栓塞治疗脑动脉瘤破裂的疗效及预后。方法:选取我院2011年至2014年期间收治的脑动脉瘤破裂患者96例作为研究对象。根据数字法随机分成观察组及对照组各48例,观察组患者在入院3d之内实施微弹簧圈栓塞形式介入治疗,对照组治疗时间为入院3 d后。对比两组患者临床治疗疗效、并发症发生情况、以及术后6个月的改良Rankin量表(m RS)、改良型日常生活能力(MBI)评分。结果:观察组的栓塞效果显著好于对照组,差异有统计学意义(P<0.05)。观察组术后6个月的m RS评分显著低于对照组,且MBI评分显著高于对照组,差异均有统计学意义(均P<0.05)。观察组的并发症发生率均显著低于对照组,差异均有统计学意义(均P<0.05)。结论:入院3d之内利用微弹簧圈栓塞对脑动脉瘤破裂实施早期介入治疗,具有较好的疗效及预后,值得临床重视。更多还原

【Abstract】 Objective: To study and analyze of the effect and prognosis of early intervention microcoil embolization(EIME) in the treatment of cerebral aneurysm rupture. Methods: A total of 96 patients with cerebral aneurysm rupture, who were admitted to Shenzhou Hospital of Hebei Province from 2011 to 2014, were selected and randomly divided into observation group(n=48) and control group(n=48). The observation group was treated with microcoil embolization intervention within 3 days after hospitalization, while the control group, 3 days after hospitalization, The clinical effect, incidence of complications, the modified Rankin scale(m RS) score and modified barthel index(MBI) score 6 months after operation in the two groups were compared. Results: The clinical effect of embolization in the observation group was better than that in the control group,the difference was statistically significant(P<0.05). The m RS score of the observation group 6 months after operation was significantly lower than that of the control group, but the MBI score was significantly higher than that of the control group, the differences were statistically significant(P<0.05). The incidence of complications in the observation group were significantly lower than that in the control group, the differences were statistically significant(P<0.05).Conclusion: Implementing the early intervention microcoil embolization within 3 days after hospitalization has a better clinical effect and prognosis in the treatment of patients with cerebral aneurysm rupture, which is worthy of attention in the clinical field.更多还原