【摘要】 目的:研究罗布麻茶和罗布麻叶对自发性高血压大鼠(SHR)生理指标的影响,并比较二者差别,为罗布麻茶作为血压调节保健食品的应用提供实验依据。方法:以SHR为实验动物,每天灌胃一次受试动物,每周测试体重,实验第6周测试血压、心率,之后采血、测血常规和血生化指标,麻醉后取脏器,计算脏器相关系数及病理学检测。结果:与对照组比,罗布麻茶和罗布麻叶显著增加嗜中性粒细胞的数量和比例,以及显著降低淋巴细胞的比例。罗布麻茶可显著降低SHR血压,降压幅度达15 mm Hg,罗布麻叶降压不明显。罗布麻叶可显著降低红细胞压积和血液中的谷草转氨酶,显著增加肾脏的脏器系数,罗布麻茶的作用不明显。结论:罗布麻茶和罗布麻叶均有调节机体免疫作用。因加工方式不同,二者相比较,罗布麻茶具有显著的降压作用,罗布麻叶有显著的降低血液黏度以及保护肝脏作用,但同时也会增加肾脏负担。更多还原

【Abstract】 Objective:Comparative study the effect of Apocynum venetum tea(Tea) and the Apocynum venetum leaves(Leaves) on the physiology of spontaneously hypertensive rats(SHR) and provide the experimental evidence for the use of Tea as a health food.Methods:SHR were fed the test substance once a day,and once a week,they were tested body weight.After six weeks,their blood pressure,heart rate,hematology,blood biochemistry,organ coefficients and pathological detection were tested.Results:Compared with the control group,both of tea and leaves increased remarkably the quantity and the rate of the neutrophilic granulocyte,and decreased significantly the rate of the lymphocyte.In addition,tea reduced blood pressure significantly by 15 mm Hg,but the leaves reduced slightly but not significantly.Leaves but not tea also produced decrease of hematocrit and glutamic oxalacetic transaminase and increase of organ coefficients of kidney.Conclusion:Both of tea and leaves can regulate the body’s immune function.Due to the different processing methods,in comparison with each other,tea has significant antihypertensive function,but the leaves has the effects of significantly decreasing of blood viscosity,protecting the liver and increasing the burden on the kidneys.更多还原