Immune-related cytokines, acting as the important component of the body's immune system, play significant roles in anti-virus, cells growth and rehabilitation of wounded tissue. Single nucleotide polymorphisms(SNPs) in cytokine genes could influence their expression level, and result in discrepancy of host serum content, the course of hepatitis virus infection and clinical prognosis. Therefore, these SNPs have a close relationship with hepatocellular carcinoma development and progression. This review summar...