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玻璃酸钠腔内注射联合得宝松治疗髋关节骨性关节炎的临床分析

Clinical analysis of intra-articular injections of sodium hyaluronate combined with diprospan in the treatment of hip osteoarthritis

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【作者】 刘建军袁普卫

【Author】 LIU Jian-jun;YUAN Pu-wei;Department of Orthopedics,Weinan Maternal and Child Health Care Hospital;Department of Orthopedics,Shaanxi University of Chinese Medicine;

【机构】 渭南市妇幼保健院骨科陕西中医药大学骨科

【摘要】 目的分析玻璃酸钠腔内注射联合得宝松对髋关节骨性关节炎的临床疗效。方法选取渭南市妇幼保健院骨科2014年1月~2015年7月收治疗的确诊为髋关节炎的患者共90例,按随机数字表法分为观察组和对照组各45例,对照组给予得宝松治疗,观察组给予玻璃酸钠腔内注射联合得宝松治疗,均治疗4周后,检测2组患者髋关节疼痛VAS评分和WOMAC评分、血脂和C反应蛋白含量、红细胞沉降率(erythrocyte sedimentation rate,ESR)和TNF-α含量的变化。结果观察组治疗后髋关节疼痛VAS评分及WOMAC评分均优于对照组(P<0.05)。观察组患者治疗后血脂和C反应蛋白分别为低于对照组(P<0.05)。观察组治疗后ESR和TNF-α分别低于对照组(P<0.05)。结论玻璃酸钠腔内注射联合得宝松治疗髋关节骨性关节炎的临床治疗效果确切。

【Abstract】 Objective To analyze effect of intra-articular injections of sodium hyaluronate combined with diprospan in the treatment of hip osteoarthritis. Methods 90 patients with hip arthritis patients from January 2014 to July 2015 were randomly divided into observation group and control group. 45 cases in each group. Control group was given Diprospan treatment,observation group was treated with articular injection of sodium hyaluronate combined with diprospan treatment. After 4 weeks of treatment,patients were followed up and recorded hip pain VAS score and WOMAC score,lipids and C-reactive protein levels,content changes in ESR and TNF-α. Results The patients after hip pain VAS score and WOMAC scores were better than control group( P < 0. 05). After observation group patients lipids and C-reactive protein were lower than control group( P < 0. 05). After treatment ESR and TNF-α of observation group were lower than control group’s( P < 0. 05). Conclusion Intra-articular injections of sodium hyaluronate combined with diprospan in treatment of hip arthritis has definite clinical effect.

【基金】 国家自然科学基金面上项目(81574006)
  • 【分类号】R684.3
  • 【被引频次】9
  • 【下载频次】92
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