【摘要】 目的探讨稳心颗粒结合美托洛尔对高血压心脏病室性早搏血液流变学和临床效果的影响。方法选取71例高血压心脏病室性早搏患者,将所选取患者按随机抽样法分为对照组34例与观察组37例。对照组予以美托洛尔,观察组在对照组基础上采予以稳心颗粒,比较2组患者的血流变水平、临床疗效及不良反应发生率。结果治疗前,2组患者全血高切黏度、全血低切黏度、血浆粘度及纤维蛋白原水平比较差异无统计学意义,治疗后,2组患者全血高切黏度、全血低切黏度、血浆粘度及纤维蛋白原水平均降低(P<0.05),治疗组各指标均低于对照组(P<0.05);观察组总有效率高于对照组(χ2=8.60,P<0.05)。2组不良反应率差异无统计学意义。结论采用稳心颗粒结合美托洛尔对高血压心脏病室性早搏患者进行治疗,能够有效改善患者血液流变学指标,且不良反应较低。更多还原

【Abstract】 Objective To investigate effect of wenxin granule combined with metoprolol on blood rheology and clinlical efficacy of patients with premature hypertension heart disease. Methods 71 cases of hypertensive patients with hypertension and ventricular premature beat were selected,and randomly divided into a control group of 34 cases and observation group of 37 cases. The control group received metoprolol,the observation group on the base of the control group with wenxin granule. Blood rheology level,clinical efficacy and adverse reaction rate were compared before and after the treatment. Results Before treatment,high blood viscosity,whole blood low shear viscosity,plasma viscosity and fibrinogen levels had no significant difference in two groups of patients. After treatment,these indexs reduced compared with the same group pre-treatment( P < 0. 05); compared with the control group,the observation group had lower blood rheology( P < 0. 05),the total effective rate was higher( χ2= 8. 60,P < 0. 05),and the incidence rate of adverse reactions was no difference. Conclusion Wenxin Granule combined with metoprolol in treatment of hypertension and ventricular premature beat patients,can improve effectively blood rheology of patients,and has low adverse reactions.更多还原