【摘要】 目的优化无糖润肺颗粒剂的醇提取生产工艺。方法采用3个不同比例的乙醇水作溶剂,选择4因素3水平正交表L9(34)进行试验,对处方中9味中药的醇溶性成分进行提取,以黄芩苷含量和干浸膏得率2者加权之和为定量指标,对影响醇提取效率的4个因素3个水平进行考察。结果醇溶性成分提取最优条件为:取9味中药先用10倍量70%乙醇浸泡45 min,再加热回流提取3次,每次1.5 h。结论本法可最大限度提取处方中9味中药的醇溶性成分,可作为润肺颗粒剂的醇提取生产工艺。更多还原

【Abstract】 Objective To optimize ethonal extraction technology for no sugar runfei granules. Methods Ethanol was used as a solvent to extract the ethanol dissolvable ingredients in 9 kinds of medicinal materials. The formula L9( 34) table was used to examine the effects of 4 factors and 3 levels. The weighted sum of baicalin content and the dried extract quantity was used as quantitative index. Results The maximize optimize condition for extraction of ethanol dissolvable ingredients was as follows: 9 kinds of medicinal materials,add of 10-fold 70% ethanol solution,soaked for 45 min,and extracted by heating reflux for 3 times,1. 5 h each time. Conclusion The method can maximize extraction of ethanol dissolvable effective ingredents in 9 kinds of medicinal materials and can be used as ethonal extraction technologgary of no sugar runfei granules.更多还原