【摘要】 目的观察上海市杨浦区美沙酮维持治疗门诊开展动机强化治疗的应用效果。方法 60名新近接受美沙酮维持治疗的海洛因依赖者被随机分为干预组(n=30)和对照组(n=30)。干预组患者接受常规美沙酮维持治疗联合12周的动机强化治疗,对照组接受常规美沙酮维持治疗。比较两组的维持治疗情况、吗啡尿检结果及成瘾严重程度指数。结果经12周动机强化治疗后,干预组与对照组平均服药天数(66 d和54 d)、尿检阴性次数(8.1次和6.2次)的差异均无统计学意义(P>0.05)。但是在24周观察期内,干预组的职业/社会支持状况、毒品使用情况、乙醇滥用情况及家庭/社会关系改善程度显著优于对照组。结论在上海市杨浦区开展的动机强化治疗未明显提高美沙酮维持治疗的依从性,但有助于美沙酮维持治疗门诊的海洛因依赖者改善其躯体健康状况、职业/社会支持状况、毒品使用严重程度。更多还原

【Abstract】 Objective To explore the effect of enhancing motivation( EM) of methadone maintenance treatment( MMT) clinic in Yangpu district of Shanghai. Methods A total of 60 heroin dependents who recently underwent MMT were randomly divided into the control group( n = 30) and intervention group( n =30). Patients of the intervention group underwent MMT and 12 weeks of EM and patients of the control group only underwent MMT. Results of MMT, morphine test, and addiction Severity Index( ASI) of two groups were com pared. Results The differences of average medication days( 66 d versus 54 d) and number of negativeurine tests( 8. 1 versus 6. 2) between two groups were not statistically significant after 12 weeks of EM( P > 0. 05). But the professional and social supports, severity of drug use, alcohol addiction, and family / society relation of the intervention group were remarkably better than those of the control group during the 24 weeks of observation. Conclusion The EM conducted in Yangpu district of Shanghai does not significantly im prove the effect of MMT, but is helpful for im proving the physical health and professional and social supports of heroin dependents, and decreasing the severity of drug use.更多还原