【摘要】 目的了解我院门诊患者药品不良反应(ADR)发生的特点和规律。方法对我院门诊药房2013年所收集的328例ADR进行统计分析。结果在328例报告中,女性发生率(70.73%)明显高于男性(29.27%);在给药方式中,口服途径引发的ADR占56.10%,静脉滴注引发的ADR占41.77%;ADR发生率最高的是心脑血管系统药物(27.74%),其次是抗菌药物(25.30%)和神经系统药物(20.43%),抗菌药物中头孢菌素类发生ADR居首位(28例),其次是大环内酯类(25例);ADR累及器官或系统ADR累及系统以消化系统损害最多,共117例(25.77%)。结论医院应加强ADR监测工作,规范临床合理用药,确保患者用药安全。更多还原

【Abstract】 Objective To investigate the characteristics and regularity of adverse drug reactions( ADR) of out-patients occurred in our hospital. Methods 328 cases of ADR cases collected in our out-patient dispensary in 2013 were analyzed retrospectively. Results In total 328 ADR cases,ADR incidence of female( 70. 73%) was obviously higher than the male( 29. 27%). 56. 10% of ADR cases were induced via oral route drugs and 41. 77% were induced via intravenous route drugs. 27. 74% of ADR cases were caused by the cardiovascular system drugs,followed by the antibiotic and cerebral system drugs. Among the antibiotic,28 cases were caused by cephalosporins and 25 cases by macrolide. The main clinical manifestations of ADR cases were injury of digestive system( 25. 77%). Conclusion More attention should be paid to the ADR monitoring to provide reference for clinical rational use of drug and ensure the safe use of drugs.更多还原