To study the effect of tributyltin chloride on amylase and lipase activity in digestive gland,Ostrea cucullata were exposed to the tributyltin chloride of six different concentrations( 0,2,5,10,50 and 100 ng·L- 1). After treatment of 1,2,3 and 4 d,the specific activities of amylase and lipase in the O. cucullata were analyzed by using enzyme analytical method respectively. It showed that( 1) TBTCL had a marked inhibition effect on amylase activity in the digestive gland( P < 0. 05) and the variation showed ...