【摘要】 目的探讨轻度胃肠炎伴婴幼儿良性惊厥的临床特点。方法对229例符合轻度胃肠炎伴婴幼儿良性惊厥的3岁内患儿的临床资料、辅助检查结果及随访资料进行回顾性分析。结果轻度胃肠炎伴婴幼儿良性惊厥在性别方面无统计学差异(χ~2=2.268,P>0.05);24月龄内发病204例(89.1%),为高发,具有统计学意义(χ~2=6.75,P<0.05);10~12月份发病89例(38.9%),1~3月份发病68例(29.7%),发病季节以冬春季为主,差异具有统计学意义(χ~2=6.38,P<0.05);158例(69%)有呕吐,其中93例(40.6%)伴有腹泻,71例(31.0%)仅有呕吐无明显腹泻;肠道病毒检测阳性32例(13.90%),呼吸道病毒检出阳性53例(27.5%);血糖、血电解质均正常,脑脊液常规、生物化学检查正常,脑脊液细菌涂片和培养均为阴性;头颅CT/MRI检查、脑电图检查,均未见异常;随访中有12例(5.2%)出现复发,10例(4.4%)出现热性惊厥,6例(2.6%)诊断为癫痫。结论轻度胃肠炎伴婴幼儿良性惊厥大多数病例预后良好,少数病例有向热性惊厥及癫痫转化的可能,应动态随访12个月。更多还原

【Abstract】 Objective To discuss the clinical features of benign infantile convulsions associated with mild gastroenteritis.Methods Retrospective analysis was conducted on clinical data,auxiliary examination results and follow-up data of 229 children under 3 years old showing benign convulsions associated with mild gastroenteritis.Results There was no statistical significance in incidence of benign infantile convulsions associated with mild gastroenteritis between genders(x~2=2.268,P >0.05).Among children under 24 months old there were 204 cases(89.1%),and the incidence was high(x~2 = 6.75,P <0.05).The onset of 89 cases(38.9%) was during October to December and 68 cases(29.7%) during January to March.Winter and spring were the frequent onset seasons with statistical significance(x~2=6.38,P <0.05).Vomiting occurred in 158 cases(69%),including 93 cases(40.6%) companied with diarrhea and71 cases(31.0%) without obvious signs of diarrhea.Enterovirus was positive in 32 cases(13.90%) and respiratoiy virus was positive in53 cases(27.5%).For all cases,blood sugar and blood electrolyte were normal,cerebrospinal fluid(CSF) kept normal,and no abnormality was found in biochemical examination.CSF culture was negative.No abnormalities were found in brain CT/MRI scan and EEG examination.In the follow- up period,there were 12 recurrent cases(5.2%) and 10 cases(4.4%) of febrile convulsion.Six cases(2.6%) were diagnosed as epilepsy.Conclusion Most cases of benign infantile convulsions associated with mild gastroenteritis obtain good prognosis.A few of them might develop into febrile convulsion or epilepsy,so dynamic follow-up lasting 12 months is necessary.更多还原