【摘要】 目的了解南安市柳城社区成人糖尿病及糖尿病前期的流行病学特点。方法采用整群随机抽样方法,于2013年调查南安市柳城社区5个村委会常住居民(40岁及以上)4 756人,应答率89.4%。受试者隔夜空腹行口服葡萄糖耐量试验,检测空腹血糖及服糖后2 h血糖以分析其糖代谢情况。调查和分析糖尿病及糖尿病前期的相关危险因素。结果糖尿病及糖尿病前期患病率分别为13.7%(男性14.6%,女性12.9%)和14.4%(男性14.3%,女性14.6%);标化后分别为8.1%(男性8.5%,女性7.7%)和8.0%(男性7.8%,女性8.1%)。糖尿病及糖尿病前期的患病率均随年龄增长而升高(P<0.05)。多因素Logistic回归分析显示增龄、家族史、肥胖、血压升高、甘油三酯升高、总胆固醇升高为糖代谢异常的危险因素(OR=2.05、3.22、1.25、1.15、1.28、1.13,P<0.05)。高密度脂蛋白、规律运动是发生糖代谢异常的保护因素(OR=0.86、0.84,P<0.05)。结论南安市柳城社区糖尿病及糖尿病前期患病率相对较低,增龄、家族史、肥胖、高血压、高血脂是糖代谢异常的危险因素。须采取有效的防治策略以干预糖代谢异常的流行。更多还原

【Abstract】 Objective To investigate the prevalence and epidemiology of diabetes mellitus(DM) and prediabetes in Nanan.Methods Cross-sectional and cluster sampling method were used in this study. A total of 4 756 residents age 40 and above were enrolled from 5 regions in Liucheng Community, Nanan, during 2013. The response rate was 89.4%. To identify undiagnosed diabetes and prediabetes, the fasting and 2-hour glucose levels were measured by 75-g oral glucose tolerance test(OGTT) after at least a 10-hour overnight fast among all participants. The related risk factors for diabetes and pre-diabetes were investigated and analyzed. Results The crude prevalenceof diabetes and prediabetes in the survey were 13.7%(14.6% among men,12.9% among women) and 14.4%(14.3%among men,14.6% among women), respectively.The standardized prevalence of total diabetes and prediabetes were 8.1%(8.5% among men, 7.7% among women) and8.0%(7.8% among men, 8.1% among women), respectively. The prevalence of diabetes and pre-diabetes are increased with age(P <0.05). Multivariate Logistic analysis showed that age, family history of diabetes, obesity, elevated blood pressure, elevated triglycerides(TG), total cholesterol(TC) were the risk factors for the glucose metabolic abnormalities;high density lipoprotein cholesterol(HDL-C), regular exercise was the protection factor. Conclusions The prevalence of DM and prediabetes are relatively low among residents in this community. Age, family history of diabetes, obesity,elevated blood pressure, TG and TC were the risk factors for the glucose metabolic abnormalities. Effective prevention and control strategies to intervene the popularity of glucose metabolism disorders are needed.更多还原