【摘要】 目的观察微波消融术对支气管结核患者的治疗效果。方法 120例支气管结核患者随机分为两组:微波消融组和对照组。微波消融组给予全身抗结核药物和微波消融术治疗,对照组则仅给予全身抗结核治疗。记录两组患者纤维支气管镜下病灶改变、临床症状好转、痰菌转阴和复发等方面情况。结果在病灶改变方面,微波消融组治愈31例,好转26例,未愈3例。对照组治愈20例,好转27例,未愈13例,微波消融组的病灶改变优于对照组(Z=-2.634,P=0.008);在临床症状方面,微波消融组显效30例,好转27例,无效3例。对照组显效22例,好转25例,无效13例。微波消融组的症状好转明显比对照组好(Z=-2.171,P=0.03)。微波消融组痰菌转阴的患者比对照组多(χ2=9.367,P=0.002)。而微波消融组复发的患者明显比对照组少(χ2=4.324,P=0.038)。结论微波消融术对支气管结核患者效果显著,副作用少。更多还原

【Abstract】 Objective To observe the effect of microwave ablation on the patients with endobronchial tuberculosis.Methods One hundred and twenty patients with endobronchial tuberculosis were divided into microwave ablation group andcontrol group. The patients in microwave ablation group were treated with oral anti-tuberculosis drugs and microwave ablation,those in the control group were treated with oral anti-tuberculosis drugs. The changes of focci in patients of two groups wereobserved under bronchofibroscope. The clinical symptoms improvement, phlegm bacterium turning negative rate and relapserate were recorded. Results As seen under bronchofibroscope,the number of cured patients,improved patients and not curedpatients in microwave ablation group were 31,26 and 3,respectively.While that in control group were 20,27,and 3. The foci inpatients of microwave ablation group were apparently improved compared to those in control group(Z=-2.634,P=0.008). Thenumber of remarkable effective patients,improved patients and non-effective patients in microwave ablation group were 30,27,and 3, respectively.While that in control group were 22,25 and 13.In microwave ablation group the clinical symptomsimprovements was superior to those in control group(Z=-2.171,P=0.03). In addition, the phlegm bacilli negative conversionrate in case of microwave ablation group was higher(χ2=9.367,P=0.002)and relapse rate was lower(χ2=4.324,P=0.038)thanthose in control group. Conclusion Microwave ablation is remarkably effective for the patients with endobronchialtuberculosis with complications were less.更多还原