【摘要】 目的 :探讨联用依达拉奉和藻酸双酯钠治疗急性脑梗死的临床效果。方法 :将我院收治的90例急性脑梗死患者纳入本研究,并随机分为观察组(46例)和对照组(44例)。两组患者入院后,我们对其均给予常规治疗。在此基础上,为对照组患者使用依达拉奉进行治疗,为观察组患者联用依达拉奉和藻酸双酯钠进行治疗。治疗结束后,比较两组患者的治疗效果。结果 :治疗前,两组患者的NIHSS评分及BI评分相比差异不具有显著性(P>0.05)。治疗后,两组患者的NIHSS评分及BI评分均有所改善,但观察组患者的NIHSS评分显著低于对照组患者,BI评分显著高于对照组患者,二者相比差异具有显著性(P<0.05)。观察组患者治疗的总有效率明显高于对照组患者,二者相比差异具有显著性(P<0.05)。在进行治疗期间,两组患者均未发生严重的不良反应,对其进行肝肾功能检查的结果显示无异常。结论 :联用依达拉奉和藻酸双酯钠治疗急性脑梗死的效果显著。此治疗方法值得在临床上推广应用。更多还原

【Abstract】 Objective: To observe the effect of Edaravone combination with Polysaccharide Sulfate in treatment of acute cerebral infarction. Methods: Total 90 patients with acute cerebral infarction were randomly divided into two groups. On the basis of conventional therapy, control group(44 cases)) were given with 30 mg Edaravone(intravenous drip, bid), while treatment group(46 cases) were given by combination with 150 mg Polysaccharide Sulfate(intravenous drip, qd) for 14 days. National Institutes of Health Stroke Scale(NIHSS) and Barthel ADL index scores(BI) were adopted to assess the curative effect for two groups. Results: The NIHSS and BI scores for two groups improved significantly after treatment, but the score for treatment group improved more than control group significantly(P<0.05). The effective percentage in treatment group(86.96%) was significantly higher than control group(72.73%)(P<0.05). Conclusion: The effect of Edaravone combination with Polysaccharide Sulfate is better than single Edaravone for treatment of acute cerebral infarction.更多还原