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联合应用醒脑静和石杉碱甲治疗血管性痴呆的效果观察

Observation of Xingnaojing combined with huperzine A on vascular dementia patients

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【作者】 沈冶军陈海洪缪抱红

【Author】 Shen-Yejun;Chen-Haihong;Miao-Baohong;Rudong County People’s Hospital;

【机构】 如东县人民医院神经内科

【摘要】 目的 :探讨联合应用醒脑静和石杉碱甲治疗血管性痴呆的效果。方法 :对2012年3月~2015年3月我院收治的46例血管性痴呆患者的临床资料进行回顾性分析,采用随机数表法将其分为对照组和观察组,每组各23例患者。为对照组患者采用石杉碱甲进行治疗,为观察组患者联合应用醒脑静和石杉碱甲进行治疗,然后对比分析两组患者的临床疗效及发生不良反应的情况。结果 :在进行治疗后,观察组患者ADL及MMSE评分的改善度优于对照组患者,其治疗的总有效率高于对照组患者,差异显著,有统计学意义(P<0.05)。两组患者在进行治疗期间均未发生明显的不良反应。结论 :联合应用醒脑静与石杉碱甲治疗血管性痴呆的效果确切,安全性较高,此法值得在临床上推广应用。

【Abstract】 Objective: To evaluate the clinical efficacy of Xingnaojing combined with huperzine A on vascular dementia. Methods: 46 patients were randomly divided into control group and observation group, 23 cases in each group. The control group were treated with huperzine A, the observation group were given Xingnaojing treatment.The daily life ability scale(ADL), the simple intelligent scale(MMSE) score, the effective rate and adverse reactions were compared. Results: After treatment, the ADL and MMSE scores of the observation group were better than those in the control group,(P< 0.05). The effective rate of observation group was higher than that of the control group(P<0.05). No obvious adverse reactions was found in the two groups during the treatment. Conclusion: The efficacy and safety of Xingnaojing combined with huperzine A on vascular dementia is good, which is worthy of clinical application.

【关键词】 血管性痴呆醒脑静石杉碱甲疗效
【Key words】 vascular dementiaXingnaojinghuperzine Acurative effect
  • 【文献出处】 当代医药论丛 ,Contemporary Medicine Forum , 编辑部邮箱 ,2015年19期
  • 【分类号】R277.7
  • 【被引频次】2
  • 【下载频次】82
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