【摘要】 目的研究降钙素原(procalcitonin,PCT)及血小板对早产儿是否发生院内感染,败血症的早期识别作用。方法回顾性分析我科2012年1月至2013年12月住院期间怀疑发生院内感染的早产儿,统计患儿胎龄、出生体重、发生感染的时间及血培养、PCT、血小板等检查结果。结果本资料127例患儿分为两组,非感染组(59例),败血症组(68例),败血症组血小板减少46例,血小板最低值:5×109/L,与非感染组血小板减少人数比较χ2=56.184,P=0.000。PCT均数(20.43±9.43)ng/ml,与非感染组降钙素原相比t=15.201,P=0.008。治愈出院65例患儿复查血培养阴性时PCT均数(0.925±0.347)ng/ml,与诊断败血症时降钙素原结果比较,t=0.837,P=0.046,血小板正常。结论 PCT、血小板改变可有效帮助识别早产儿院内感染:败血症。更多还原

【Abstract】 Objective To research the role in early recognition of procalcitonin( PCT) and platelet in premature infants on nosocomial infection. Methods A retrospective analysis was performed in premature infants who was suspected nosocomial infection on clinical date 2012 January to 2013 December,collecting the results of the gestational age,birth weight,the time of infection,blood culture,platelet. Results According to the last diagnosis,127 cases of premature babies divided to two groups: non-infected group( 59),spesis group( 68).sepsis group,the platelet of 46 cases was reduced,the minimum: 2. 8 × 109/ L,compared with non-infected groupχ2= 56. 184,P = 0. 000. the mean of spesis was 26. 43 ± 9. 43 ng / ml,compared with non-infected group t = 15.201,P = 0. 008. the mean of PCT of 65 case cured while blood culture was negative was 0. 925 ± 0. 347 ng / ml,compared with non-infected group t = 0. 837,P = 0. 046,platelet was normal. Conclusions PCT,platelets change can effectively help recognize nosocomial infections in preterm children: sepsis.更多还原