【摘要】 该文提出一种马赛克式正电子发射断层成像(PET)探测器设计方案,通过改变晶体的排布方式,并基于GATE(Geant4Application for Emission Tomography)软件模拟,对3种马赛克PET的设计方案和传统的PET设计方案进行了多方面的对比,对比的内容包括:轴向探测效率、体源探测效率以及空间分辨率。并且进一步考虑能量下阈的影响,比较能量下阈为0keV、250keV和350keV时各个方案测得的结果的变化。结果表明:马赛克PET方案在不考虑能量下域时,轴向探测效率提高24%~50%,而体源探测效率更是可以提高47%~62%。当能量下阈为250keV时,方案4的轴向探测效率和体源探测效率可分别提升12%和8%,于此同时其重建图像空间分辨率较传统方案相比接近。更多还原

【Abstract】 There positron emission tomography(PET) mosaic designs were developed from a traditional PET design based on GATE(Geant4Application for Emission Tomography)simulations using axial sensitivity,volume sensitivity and spatial resolutions with various energy thresholds of 0keV,250 keV and 350 keV.The results indicate that without the effect of the energy threshold,the axial sensitivity of the mosaic designs is increased 24%-50%,while the volume sensitivity is increased 47%-62%.With an appropriate energy threshold(250keV),the axial sensitivity is increased by12% while the volume sensitivity is increased by 8% to give similar image quality as the traditional design.更多还原