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联合手术对肝癌合并门静脉高压症的实效性探究

Effectiveness of combined surgery for hepatocellular carcinoma combined with portal hypertension

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【作者】 吴跃锐龚建安谭晓宇

【Author】 WU Yue-rui;GONG Jian-an;TAN Xiao-yu;Guizhou Hospital,Shunde District,Foshan,Guangdong;

【机构】 广东省佛山市顺德区桂洲医院外三科广州军区广州总医院肝胆外科

【摘要】 目的探讨并分析联合手术对肝癌合并门静脉高压症患者的术后恢复效果及死亡率。方法回顾性分析在我院接受治疗的肝癌合并门静脉高压症的35例患者,并在术后5年内对患者进行随访调查死亡率以及对死亡原因进行统计。结果经过联合手术后35例患者的血小板和白细胞计数恢复正常。所有患者的血小板和白细胞计数较术前均有提高,差异具有统计学意义(P<0.05)。对所有35例患者进行随访,1年、2年、3年和5年内死亡的患者分别为3例、5例、10例和18例,5年内生存率为48.57%;死亡原因包括肝癌复发转移死亡患者11例,肝功能衰竭死亡患者4例,上消化道出血死亡患者3例。结论对肝癌合并门静脉高压症患者实施联合治疗方式安全可行,值得进一步推广使用。

【Abstract】 Objective To observe and explore postoperative recovery effects and mortality of combined surgery for hepatocellular carcinoma combined with portal hypertension.Methods Totally35 patients with hepatocellular carcinoma combined with portal hypertension in our hospital were followed up for five years,and mortality and causes of death were investigated.Results Totally35patients’ platelet and leukocyte counts returned to normal after combined surgery.Platelet and white blood cell count of all patients were significantly improved(P<0.05).All 35 patients were followed up,3cases,5cases,10 cases and 18 cases were died at 1,2,3and 5years later,respectively,five-year survival rate was 48.57%;death reasons,including 11 patients died by liver cancer recurrence,four cases died by liver failure,three cases died by upper gastrointestinal bleeding.Conclusion Combined surgery is safe and feasible for patients with hepatocellular carcinoma combined with portal hypertension,it is worth further promoting the use.

【基金】 广东省2014医学科研基金立项(B2014315)
  • 【文献出处】 青岛医药卫生 ,Qingdao Medical Journal , 编辑部邮箱 ,2015年03期
  • 【分类号】R735.7
  • 【被引频次】2
  • 【下载频次】28
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