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抗生素所致不良反应及临床合理用药分析

Analysis of adverse reactions caused by antibiotics and clinical rational drug use

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【作者】 向斌向艳

【Author】 XIANG Bin;XIANG Yan;Life Science and Technology College of China Pharmaceutical University;

【机构】 中国药科大学生命科学与技术学院南华大学公共卫生学院

【摘要】 目的分析抗生素所致不良反应及临床合理用药。方法选取2013—2014年南华大学附属医院收治的抗生素所致不良反应患者92例,对其临床资料进行回顾性分析。结果抗生素所致不良反应中61~76岁组所占比例最高(P<0.05);不良反应的药物种类中头孢菌素类所占比例最高(P<0.05);不良反应主要累及皮肤及其附件(P<0.05)。结论抗生素所致不良反应种类较多,且发生率较高,加强临床合理用药,可减少不良反应的发生,提高用药安全。

【Abstract】 Objective To analyze adverse reactions caused by antibiotics and clinical rational drug use. Methods A total of 92 patients with adverse reactions caused by antibiotics were selected in the Affiliated Hospital of University of South China from 2013 to 2014,clinical data was retrospectively analyzed. Results Of the adverse reactions caused,antibiotics by the highest proportion was 61- 76 age group( P < 0. 05); of the adverse reactions of drug variety,the highest proportion was cephalosporin class( P < 0. 05); adverse reactions mainly involved the skin and accessories( P < 0. 05). Conclusion Antibiotic adverse reactions caused by antibiotics is more and the incidence is higher,strengthen the clinical rational drug use can reduce the occurrence of adverse reactions and improve medication safety.

【关键词】 药物毒性抗菌药合理用药
【Key words】 Drug toxicityAnti-bacterial agentsRational drug use
  • 【文献出处】 临床合理用药杂志 ,Chinese Journal of Clinical Rational Drug Use , 编辑部邮箱 ,2015年21期
  • 【分类号】R595.3
  • 【被引频次】6
  • 【下载频次】167
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