【摘要】 目的调查医院神经内科苦碟子注射液的使用情况,为临床合理使用苦碟了注射液提供参考。方法利用Excel软件对医院神经内科2013年上半年使用苦碟子注射液208例的适应证、用法用量、疗程、溶媒、联合用药及不良反应进行统计分析。结果神经内科苦碟子注射液主要用于脑梗死(使用率48.08%)、椎基底动脉供血不足或短暂性供血不足(使用率16.35%)、神经症(使用率9.13%)、脑炎(使用率7.21%)等;用药浓度>10ml/100ml的占97.60%,而用药浓度≤10ml/100ml只占2.40%;用药疗程<14d的占76.44%,用药疗程=14d的占3.37%,用药疗程>14d的占20.19%;无不当联用药物;2例出现了不良反应,占0.96%。结论神经内科使用苦碟子注射液基本合理,主要存在问题为输液溶媒用量偏小,导致药物浓度偏高,少数存在超说明书用药问题。更多还原

【Abstract】 Objective To investigate the use of Kudiezi Injection in neurology department,in order to provide the reference for the clinical rational use of Kudiezi injection. Methods The indications,usage and dosage,course of treatment,solvent,combined therapy and adverse reaction of Kudiezi Injection in neurology department in our hospital during the first half of2013 were analyzed statistically by using excel software. Results Kudiezi Injection was mainly used for cerebral infarction( 48. 08%),vertebrobasilar artery insufficiency or transient insufficiency( 16. 35%),neurosis( 9. 13%),ncephalitis( 7. 21%) in neurology department of internal medicine. The drug concentration > 10ml/100 ml accounted for 97. 60%,and the drug concentration was less than or equal to 10 ml /100 ml accounted for 2. 40%. The course of treatment of less than 14 days accounted for 76. 44%; equal to 14 day accounted for 3. 37%,and greater than 14 days accounted for 20. 19%. There was no improper drug combination. The adverse reactions events occurred in 2 cases,accounting for 0. 96%. Conclusion The use of Kudiezi Injection is basically reasonable. And the main existing problems is that the transfusion menstruum dosage is too small,which leads to higher drug concentration,and few existing off-label drug use.更多还原