【摘要】 目的探讨最大颈动脉内膜中层厚度(cIMT)对冠心病(冠心病)的诊断预测作用。方法将无冠心病病史的184例病人以冠脉CT或冠脉造影证实冠状动脉狭窄≥50%为标准分为冠心病组76例和无冠心病组108例。记录血压及血脂水平,测量最大cIMT数值。结果冠心病组中最大cIMT明显大于非冠心病组,差异具有统计学意义(1.10±0.3)vs(0.99±0.3),P<0.01。将入组的冠心病危险因素、最大cIMT进行logistic回归法分析,发现最大cIMT(OR=2.796,95%CI 1.446~5.334,P<0.01)与冠心病的发生明显相关,是冠心病的强预测因素。结论 cIMT与冠心病的发生明显相关,可以作为冠心病新的危险因素应用于临床。更多还原

【Abstract】 Objective The purpose of this study was to evaluatethe value of maximum carotid intima-media thickness(cIMT)for predicting coronary artery disease(CAD).Methods 184 patients with no history of coronary heart disease underwent computed tomography angiography or coronary angiography.And then divided into CAD group(n=76)and non-CAD group(n=108)which due to coronary artery stenosis≥50%,and measured blood pressure and blood fat,measuring maximum cIMT.Results Maximum cIMT was significantly higher in CAD group than which in non-CAD group(1.10±0.3vs0.99±0.3,P<0.01).Multiple logistic regression analysis reveals thatcIMT(OR=2.796,95%CI 1.446~5.334,P<0.01)were associated with CAD,whichwere stronger predictor of.Conclusion CIMT was significantly related with the incidence of CHD which could be used as a new risk factor of coronary heart disease(CHD)for clinical application.更多还原