【摘要】 目的:研究鲑鱼降钙素联合阿仑膦酸钠治疗老年性骨质疏松,对骨密度和血清1,25-(OH)2D3的影响。方法:将接受我科治疗的老年性骨质疏松患者90例,分为对照组45例,给予口服阿仑膦酸钠70mg/周治疗,治疗组45例,给予阿仑膦酸钠治疗基础上加用鲑鱼降钙素鼻喷剂1次/天治疗,治疗半年后观察两组患者临床症状、骨密度的变化、血清1,25-(OH)2D3的变化。结果:两组患者临床症状均有所好转,治疗组患者骨密度水平高于对照组,差异有统计学意义(<0.05);治疗组患者血清1,25-(OH)2D3水平显著高于对照组,差异有统计学意义(<0.05)。结论:鲑鱼降钙素联合阿仑膦酸钠治疗骨质疏松症患者,可以更好地改善骨密度,提高血清1,25-(OH)2D3水平。更多还原

【Abstract】 Objective: Study of salmon calcitonin and Allen phosphonic acid sodium treatment for senile osteoporosis,Effects on bone mineral density and 1,25-(OH)2D3.Methods: For treatment of 90 cases of senile osteoporosis patients,divided into the control group 45 cases,give oral alendronate sodium phosphonic acid 70mg/weeks,the treatment group 45 examples,give Allen phosphonic acid sodium joint salmon calcitonin treatment,six m onths after treatment to observe two groups of patients with clinical symptoms,the changes of bone mineral density an d serum 1,25-(OH)2D3. Results:Two groups of patients with clinical symptoms were improved,the treatment group patients with bone mineral density is higher than the control group,the difference was statistically significant( <0.05),the treatment group patients serum 1,25-(OH)2D3levels higher than the control group,the difference was statis tically significant( <0.05).Conclusion: Salmon calcitonin joint Allen phosphonic acid sodium in the treatment of osteoporosis patients,improve bone mineral density,improve the level of serum 1,25-(OH)2D3.更多还原