Objective:To discuss the effect of Jujing Granule on oligoasthenozoospermia and PRM2 mRNA expression level.Methods:Jujing Granule was used to treat 21 cases of oligoasthenozoospermia patients and 8 cases with normal sperm were selected.We compared the changes of sperm concentration,vitality and PRM2 mRNA level between each of them and normal persons before and after treatment.Results:PRM2 mRNA level was lower than that of the normal persons before treatment(P < 0.05),but there was no statistical difference ...