Two-dimension speckle tracking imaging assessment of right ventricular function in patients with acute inferior and anterior myocardial infarction

【摘要】 Background Acute inferior and anterior myocardial infarction often leads to right ventricular(RV)function decrease. Estimation of RV function is challenging due to the complex RV geometry. Few studies have been conducted to investiogate the effects of acute myocardial infarction(AMI)on right ventricular functions(RVFs). Two-dimension Speckle Tracking Imaging(STI) is a novel method that allows for a segment based measurement of myocardial deformation and may have the potential to quantify RV dysfunction more precisely than the conventional parameters of RV function. Therefore, in this study we analyzed the RV function in AMI patients by using this novel technique. Methods Thirty-four patients with acute inferior myocardial infarction(AIMI), 31 patients with acute anterior myocardial infarction(AAMI and 30 agematched healthy individuals were enrolled for the study. 2D speckle tracking imaging(STI) was used to obtain2 D imaging at the apical four- chamber view under rest condition. Peak systolic strains and strain rates of all segments in right ventricular free wall were analyzed. Results Compared to the normal control group,longitudinal peak systolic strain(ε), strain rate(SRs), early diastolic strain rate(SRe) and late diastolic strain rate(SRa) in all segments of right ventricular free wall were significantly lower in AMI patients. ε,SRs, SRe and SRa of each segment of RV in the AIMI group were decreased significantly than those of the normal control group(P < 0.05). ε, SRs, SRe and SRa of each segment of RV in the AAMI group were lower than these in the control group. Except for basal segmental SRa, there were significant differences among other parameters(P < 0.05). Conclusions RVFs are impaired in AMI patients. RVFs could be accurately and sensitively assessed with STI.更多还原

【Abstract】 Background Acute inferior and anterior myocardial infarction often leads to right ventricular(RV)function decrease. Estimation of RV function is challenging due to the complex RV geometry. Few studies have been conducted to investiogate the effects of acute myocardial infarction(AMI)on right ventricular functions(RVFs). Two-dimension Speckle Tracking Imaging(STI) is a novel method that allows for a segment based measurement of myocardial deformation and may have the potential to quantify RV dysfunction more precisely than the conventional parameters of RV function. Therefore, in this study we analyzed the RV function in AMI patients by using this novel technique. Methods Thirty-four patients with acute inferior myocardial infarction(AIMI), 31 patients with acute anterior myocardial infarction(AAMI and 30 agematched healthy individuals were enrolled for the study. 2D speckle tracking imaging(STI) was used to obtain2 D imaging at the apical four- chamber view under rest condition. Peak systolic strains and strain rates of all segments in right ventricular free wall were analyzed. Results Compared to the normal control group,longitudinal peak systolic strain(ε), strain rate(SRs), early diastolic strain rate(SRe) and late diastolic strain rate(SRa) in all segments of right ventricular free wall were significantly lower in AMI patients. ε,SRs, SRe and SRa of each segment of RV in the AIMI group were decreased significantly than those of the normal control group(P < 0.05). ε, SRs, SRe and SRa of each segment of RV in the AAMI group were lower than these in the control group. Except for basal segmental SRa, there were significant differences among other parameters(P < 0.05). Conclusions RVFs are impaired in AMI patients. RVFs could be accurately and sensitively assessed with STI.更多还原