【摘要】 目的 探讨T2 mapping序列对强直性脊柱炎(AS)的早期诊断价值。方法 收集有慢性炎性下腰痛症状的患者50例,其中临床诊断为AS的36例,另14例诊断为单纯慢性下腰痛(LBP)。所有患者均进行骶髂关节常规序列及8回波T2m印ping序列的扫描,分别测量两组患者双侧骶髂骨骨性关节面下骨髓的T2值,并进行统计学分析。结果 AS组左、右侧及双侧骶骨T2值与LBP组比较差异无统计学意义。AS组左、右侧及双侧髂骨T2值均大于LBP组(P<0.05),差异有统计学意义。36例AS患者中的26例中共发现60处病灶,病灶与其周围相对正常组织比较,差异有显著性(p=0.000)。结论 T2 mapping序列可早期发现骶髂关节骨髓T2值的改变,可对AS早期骨髓病变与单纯的慢性下腰痛患者进行鉴别,有利于患者的早期诊断。更多还原

【Abstract】 Objective To investigate the value of T2 mapping sequence in early diagnosis of ankylosing spondylitis.Methods 50 patients with chronic inflamatory low back pain symptoms were collected in this study,out of which 36 patients were clinically diagnosed as AS and the remaining14 as simple chronic low back pain(LBP).Images were obtained using a 1.5T MR scanner HDxt GE.The sequences included traditional sequences and 8 echo T2 mapping sequence.T2 values of subchondral bone morrow in bilateral ilium and sacrum along the sacroiliac joint were measured using GE AW4.4 post-processing workstation.An independent two sample t-test(SPSS Version 18) was used to statistically analyse the difference of T2 values between AS and LBP patients with P value of<0.05 as the level of statistically significant different.Results There was no statistically significant difference between the AS and LBP group of the mean T2 values in bilateral sacrum.The mean T2 values in bilateral iliac bone marrow of AS patients were higher than the LBP patients(P<0.05).There were 26 patients with a total of 60 lesions in 36 AS patients.The mean T2 values of the lesions were higher than the neighboring relatively normal tissues.(P<0.05).Conclusion T2 mapping sequence could detect the early change of the T2 values of bone marrow,by which early bone marrow lesions of ankylosing spondylitis could be detected and we could use this technology to differentiate simple chronic low back pain and AS patients.更多还原