【摘要】 目的探讨感染性眼内炎患者的致病因素和临床治疗效果。方法回顾性分析安徽省立医院2013年1月至2014年6月收治的29例(29只眼)感染性眼内炎患者,分析其致病原因、治疗方法和治疗效果。结果29例感染性眼内炎患者主要致病原因是内眼手术(55.2%)和眼外伤(37.9%);病原体检出率为24.1%,主要致病菌是革兰阳性球菌,以表皮葡萄球菌为多见;7只眼行前房冲洗联合玻璃体腔注药术,6只眼行单纯玻璃体腔注药术,15只眼行玻璃体视网膜联合手术,1只眼行眼内容剜除术,治疗结束共2只眼因感染无法控制而行眼内容剜除术,眼球保存率93.1%,术后平均最佳矫正视力为2.8±1.4,较术前明显提高(1.6±1.0),有统计学意义(t=-6.6,P<0.01)。结论感染性眼内炎常见的致病因素有眼外伤和内眼手术,常见的病原体为革兰阳性球菌,治疗上根据眼内炎的严重程度而采用合适的治疗方案,是控制炎症,挽救视功能的有效措施。更多还原

【Abstract】 Objective To analyze the etiology and treatment outcome in 29 patients(29 eyes)with infectious endophthalmitis. Methods This retrospective study reviewed medical records of 29 patients(29 eyes) treated in Anhui Provincial Hospital from January 2013 to June 2014. Causes and treatment outcomes were analyzed. Results The major causes of infectious endophthalmitis were intraocular surgery(55. 2%) and ocular trauma(37. 9%). Pathogens were identified in 24. 1% of the cases and most common bacteria were Gram-positive cocci,particularly Staphylococci. Seven patients received anterior chamber irrigation combined with intravitreal injection,6 patients underwent simple intravitreal injection,and 15 patients received vitreous-retinal surgery. There were 3 patients who received evisceration surgery,among whom two were due to uncontrolled infection. The overall rate of eye preservation was 93. 1%. Mean best corrected visual acuity was2. 8 ± 1. 4,which was significantly better than preoperative(1. 6 ± 1. 0) visual acuity( t =- 6. 6,P < 0. 01). Conclusion The major causes of infectious endophthalmitis are ocular trauma and intraocular surgery. The most common bacteria are Gram-positive cocci. Appropriate treatment regimen is important to control inflammation and to save visual function.更多还原