【摘要】 目的:了解原发性肾病综合征的免疫抑制治疗进展。方法:复习近年来发表的原发性肾病综合征诊断和治疗的中英文文献。结果:原发性肾病综合征是成人原发性肾小球疾病的最常见临床表现类型,免疫抑制治疗是治疗这一综合征的主要治疗。常用的免疫抑制剂包括糖皮质激素、环磷酰胺、环孢素、他克莫司、吗替麦考酚酯和来氟米特。结论:临床医生应该根据不同病理类型选择个体化的免疫抑制治疗方案。更多还原

【Abstract】 Objective: To investigate the developments of immunosuppressive drugs in the treatment of primary nephritic syndrome. Methods: Diagnosis, as well as treatment of primary nephritic syndrome are discussed with respect to the current literatures. Results: Primary nephroic syndrome is the most common presenting pattern of primary glomerular diseases.Immunosuppressive treatment is the main therapy for this syndrome. Corticosteroids, cyclophosphamide, cyclosporine A, tacrolimus, mycophenolate mofetil, and leflunomide have all been used in treating this syndrome. Conclusion: The immunosuppressive regimen should be chosen individually based on the pathological diagnosis.更多还原