【摘要】 [目的]研究肝硬化死亡患者营养相关指标。[方法]对50例肝硬化死亡患者临终前营养相关生化指标进行回顾性分析,依据凝血酶原活动度(PTA)水平分组,PTA>40%(未合并肝功能衰竭)为A组,PTA≤40%(合并肝功能衰竭)为B组,采用统计学方法对2组资料进行计量资料的t检验。[结果]A组:MELD(12.76±6.25)分、PTA(59.66±15.87)%、总胆红素(53.28±63.68)μmol/L、直接胆红素(32.66±38.70)μmol/L、白蛋白(22.87±3.84)g/L、前白蛋白(70.63±25.01)mg/L、淋巴细胞计数(0.87±0.38)×109/L;B组:MELD(27.89±9.88)分、PTA(22.71±8.20)%、总胆红素(260.25±186.36)μmol/L、直接胆红素(167.49±136.30)μmol/L、白蛋白(23.17±4.18)g/L、前白蛋白(49.39±39.87)mg/L、淋巴细胞计数(1.75±3.44)×109/L。2组MELD评分、总胆红素、直接胆红素比较差异有统计学意义(P<0.05),2组营养学指标白蛋白、前白蛋白指标及淋巴细胞计数比较均差异无统计学意义(P>0.05)。[结论]所有肝硬化死亡的患者无论PTA%大小,均存在严重白蛋白、前白蛋白、总淋巴细胞计计数下降等营养不良状况。更多还原

【Abstract】 [Objective]To study the nutrition related indicators in liver cirrhosis patients death.[Methods]The final nutrition related index before the death in Fifty cases of liver cirrhosis patients were analyzed retrospectively.According to the prothrombin activity(PTA),the patients were divided into uncombination liver failure group(PTA>40%,A group),and combination of liver function failure)for another group(PTA 40% or less,B group).The data were compared by t test.[Results]In A group,MELD score was(12.76 ±6.25),PTA was(59.66±15.87)%,total bilirubin was(53.28±63.68)μmol/L,direct bilirubin was(32.66 ±38.70)μmol/L,albumin propagated was(22.87 ±3.84)g/L,prealbumin was(70.63±25.01)mg/L,lymphocyte count was(0.87± 0.38)× 109/L.In B group,MELD score was(27.89 ±9.88),PTA was(22.71 ± 8.20)%,total bilirubin was(260.25 ±186.36)μmol/L,direct bilirubin was(167.49±136.30)μmol/L,albumin propagated was(23.17 ±4.18)g/L,prealbumin was(49.39±39.87)mg/L,lymphocyte count was(1.75 ±3.44)×109/L.The end-stage score,total bilirubin,direct bilirubin between the two groups had significant difference(P< 0.05).The nutrition indicators of albumin,prealbumin index,lymphocyte count in the two groups had no significant difference,P> 0.05.[Conclusion]All the patients with liver cirrhosis death,regardless of the size of PTA %,have severe decrease of albumin,prealbumin,total lymphocyte count and malnutrition.更多还原