【摘要】 目的 比较肠内营养(EN)、EN联合肠外营养(PN)在胰十二指肠切除术(PD)后患者中的应用。方法 回顾性分析2005年1月~2014年1月我院87例PD后患者的临床资料,根据术后营养方式分为EN组(37例)及EN+PN组(50例),比较两组患者术后恢复情况、手术及术后营养相关并发症发生率、血生化相关性指标。结果 两组患者术后恢复情况及手术相关并发症发生率比较,差异无统计学意义(P>0.05),EN组与EN+PN组营养支持相关并发症率分别为30%、12%,差异有统计学意义(P<0.05),EN+PN组血清总胆红素、丙氨酸转氨酶高于EN组(均P<0.05),但两组均在正常值范围内。结论 PD患者术后应用EN联合PN安全性及实用性均与单独应用EN相似,但可明显减少营养相关并发症,是PD术后更好的营养方式。更多还原

【Abstract】 Objective To compare enteral nutrition(EN) vs.combined enteral nutrition and parenteral nutrition(EN +PN)in post-pancreaticoduodenectomy(PD) patients.Methods A retrospective analysis of 87 patients who underwent PD in our hospital from January 2005 to January 2014 was performed.These patients were divided into EN group(37 cases) and EN + PN group(50 cases) according to the postoperative nutritional method.The data of post-operative recovery and complications(surgery-related and nutritional) and blood biochemical index were analyzed.Results No significant difference was noted in overall complications or post-operative recovery between the two groups.The nutrition-related complications rate was 30%in EN group and 12%in EN + PN group(χ~2 = 4.25,P = 0.037).Although the liver function index(TBIL and ALT) were higher in EN + PN group(P < 0.05),there was no abnormal liver function in either groups.Conclusion EN combined with PN is as safe and practical as EN in PD patients,with fewer nutrition-related complications and better application value,and hence may be a better way of nutrition support for PD patients.更多还原