【摘要】 自噬是广泛存在于真核细胞内,通过溶酶体清除自身受损细胞器和异常蛋白的过程。在神经系统中,从神经退行性疾病到神经创伤,自噬都发挥了重要作用。深入研究神经细胞自噬发生及其分子调控机制,对全面了解自噬在神经系统疾病中的作用有重要意义。更多还原

【Abstract】 Autophagy as a degradative process that widely exists in eukaryotic cells can clear intracellular damaged organelles and protein through lysosomes. It was found in recent studies that autophagy play an important role in neurological disease, both neurodegenerative and neurotraumatic diseases. Comprehensive understanding of autophagy effect and molecular mechanism in different types of neurological diseases can provide new strategies for disease prevention and the treatment. This review mainly focused on the influence of autophagy on neurological diseases.更多还原