【摘要】 目的应用实时三维超声心动图(RT-3DE)评价糖耐量异常患者左室功能及心肌质量的情况。方法选取我院门诊及住院糖耐量异常患者70例(糖耐量异常组)和健康对照组70例,应用RT-3DE检测两组左室心肌质量指数(LVMI)、左室舒张末容积指数(LVEDVI)、左室每搏指数(LVSVI)及左室射血分数(LVEF)。同时组织多普勒成像检测左室舒张功能参数Ea、Aa及Ea/Aa,比较两组上述各指标。结果糖耐量异常组Aa较健康对照组偏大(P<0.05),Ea、Ea/Aa较健康对照偏小(均P<0.05),而两组LVEDVI、LVSVI、LVEF无明显差异,但糖耐量异常组的LVMI较健康对照组偏高(P<0.05),且与患者的血糖水平呈正相关(r=0.557,P<0.05)。结论糖耐量异常可以导致患者左室心肌重塑,影响患者的左室舒张功能。更多还原

【Abstract】 Objective To investigate the function and myocardia mass of left ventricle in patients with abnormal glucose tolerance by real-time three-dimensional ultrasound(RT-3DE).Methods Seventy cases with abnormal glucose tolerance and 70 age and sex-matched healthy controls were involved in this study.RT-3DE was used to measure LVMI,LVEDVI,LVSVI and LVEF.Meanwhile,tissue Doppler imaging was used to measure Ea,Aa and Ea/Aa.Results Aa was increased in patients with abnormal glucose tolerance compared to controls(P<0.05),while Ea and Ea/Aa were decreased in patients with abnormal glucose tolerance when compared to healthy controls(all P<0.05).There were no difference in LVEDVI,LVSVI and LVEF between two groups.In addition,LVMI of patients with abnormal glucose tolerance was increased when compared to the controls(P<0.05).There was a positive correlation between LVMI and glucose levels(r=0.557,P<0.05).Conclusion Abnormal glucose tolerance can induce myocardial remodeling and affect the left ventricular diastolic function.更多还原