【摘要】 目的探讨经桡动脉冠脉旋磨治疗严重冠脉钙化病变的疗效及安全.方法 24例严重冠状动脉钙化病变患者,随机分为经桡动脉和经股动脉旋磨治疗2组,比较2组患者的旋磨参数、支架植入成功率和术后并发症,患者术后随访1 a,随访心血管事件发生率(包括急性心梗、再次PCI及死亡).结果 2组病患手术全部成功,术中无死亡、心肌梗死和冠脉穿孔等并发症发生.经桡动脉组选用指引导管直径相对较小,穿刺并发症显著降低、卧床和住院时间明显少于股动脉旋磨组(P<0.01),2组患者所选旋磨参数、手术成功率和并发症以及远期不良心血管事件无显著差异(P>0.05).结论经桡动脉冠脉旋磨治疗严重冠脉钙化病变同股动脉组比较疗效相当、安全性相同;并且患者舒适度显著改善、术后穿刺并发症低、明显减少卧床时间和住院天数.更多还原

【Abstract】 Objectives To investigate the safety and efficacy of trans radial artery coronary rotational atherectomy in the treatment of coronary artery calcification lesions compared to trans femoral artery pathway.Methods Clinical data of 24 patients in two groups including trans radial artery coronary rotational atherectomy group(radial group) and trans femoral artery coronary rotational atherectomy group(femoral group) were analyzed. Parameters of rotational atherectomy,procedural success rate,clinical effect of postoperative visiting and main adverse cardiovascular events(including acute myocardialinfarction, stent again and death) were recorded followed up.Results Procedural success was achieved in the two groups.No main adverse cardiovascular events(including cardiac death, Q wave myocardial infarction and emergency coronary surgery) occurred during operation. The guiding catheter used in radial group was smaller than in femoral group operation. Trans-radial rotational atherectomy was associated with a decrease in access site complications, average time of lying in bed and hospitalization than in femoral group(P<0.01).Total main adverse cardiovascular events of twelve months from operation were similar. Conclusion Coronary rotational atherectomy from radial artery was safety and effective in serious coronary artery calcification lesions. It can be generalizationaly used.更多还原