【摘要】 目的利用经颅多普勒超声检测评估颅内外动脉粥样硬化性狭窄的分布特征,并探讨其危险因素。方法利用经颅多普勒超声筛查出颅内外动脉狭窄患者131例,记录其血管疾病相关病史,并探索各危险因素的影响。结果 131例动脉狭窄患者中,114例(85.5%)有颅内动脉狭窄,26例(19.8%)有颅外动脉狭窄,颅内动脉狭窄明显高于颅外动脉狭窄(χ2=118.790,P=0.000)。其中大脑中动脉是最常受累的动脉(64.2%)。Logistic二元回归分析显示高血压、糖尿病、吸烟是颅内外动脉粥样硬化性狭窄的独立危险因素。结论长期高血压、糖尿病、吸烟是颅内外动脉粥样硬化性狭窄的高危因素,提示对上述高危患者应常规进行经颅多普勒超声检测。更多还原

【Abstract】 Aim To detect the distribution of cervicocerebral arteriostenosis and evaluate its risk factors.Methods A total of 131 patients with intracranial and extracranial arteriostenosis were examined with transcranial Doppler ultrasonography( TCD). Potential risk factors for vascular disease in each patient were evaluated based on their medical history. Then the effects of related factors on arteriostenosis were probed. Results Intracranial arteriostenosis was found in 114 out of 131 patients( 85. 5%),which was significantly higher than extracranial artery stenosis or occlusion( 26 /131,19. 8%,χ2= 118. 790,P = 0. 000). The middle cerebral artery was affected in 84 patients( 64. 2%),which is the most frequently affected artery,accounting for 52. 7% in all stenotic arteries. Binary logistic regression analysis showed that hypertension,diabetes and smoking were independent factors significantly associated with cervicocerebral arteriostenosis. Conclusions Hypertension,diabetes and smoking were independent factors significantly associated with cervicocerebral arteriostenosis. Transcranial Doppler ultrasonography should be performed in these patients routinely.更多还原