【摘要】 目的评价热感糖浆治疗普通感冒(风热证)的临床疗效及安全性。方法本研究采用随机、双盲、安慰剂对照、多中心的设计方法,随机分为3组。A组78例(小剂量组)口服热感糖浆+热感糖浆模拟剂30 m L/次(含热感糖浆20 m L);B组76例(大剂量组)口服热感糖浆30 m L/次;C组79例(安慰剂组)口服热感糖浆模拟剂30 m L/次,每日4次,疗程为5 d。结果 A组和B组在中医证候疗效、症状消失时间、体温起效时间及解热时间上明显优于C组,其中B组在咽痛单项症状消失率、体温累积起效率、解热率等方面优于A组,在体温低于38℃时A,B组解热时间明显优于C组。在研究过程中,未发生严重不良事件。结论热感糖浆是治疗普通感冒(风热证)安全有效的药物。更多还原

【Abstract】 Objective To evaluate the clinical effect and safety of Regan Tangjiang in the treatment of common cold( wind heat syndrome). Methods A randomized,double-blind,placebo-controlled and multi-center design method was used in this study. The patients were randomly divided into 3 groups.Group A( low-dose group,n = 78) was given oral Regan Tangjiang and Regan Tangjiang simulation regent,30 m L every time( including 20 m L Regan Tangjiang); group B( high-dose group n = 76) was given oral Regan Tangjiang,30 m L every time; group C( placebo group n = 79) was given oral Regan Tangjiang simulation regent,30 m L every time,4 times per day,the treatment course was 5 d. Results Group A and B were superior to group C in terms of TCM syndrome,symptom disappearance time,temperature onset time and antipyretic time. Pharyngalgia elimination coefficient,accumulated temperature efficiency and antipyretic rate of group B was superior to group A. When the body temperature was lower than38 ℃,antipyretic time of group B was superior to group C. No serious adverse event happened during the study. Conclusion Regan Tangjiang is an effective and safe medicine for common cold( wind heat syndrome).更多还原