【摘要】 目的探讨急性心力衰竭(AHF)与红细胞分布宽度(RDW)水平的相关性。方法研究对象为广州市第一人民医院近1年来临床表现为气促、呼吸困难的急诊患者154例,就诊后行全血细胞计数检测和N端脑钠脲肽前体(NT-ProBNP)检测。分为AHF患者组[87例,按心功能分级分为Ⅰ级(n=8)、Ⅱ级(n=10)、Ⅲ级(n=36)、Ⅳ级(n=33)]和非AHF组(67例,排除心源性疾病)。结果 (1)AHF组和非AHF组RDW水平比较差异有统计学意义(P<0.05),且随NYHA心功能分级级数的增高而增高。(2)RDW与NT-ProBNP的水平具有相关性,呈正相关。结论 AHF患者升高的NT-ProBNP与RDW是正相关的,RDW与急性心力衰竭严重程度密切相关,RDW结合NT-ProBNP可作为急性心力衰竭低廉、简易的辅助预测因子,也可用于临床心力衰竭分级。更多还原

【Abstract】 Objective To study the correlation between red blood cell distribution width(RDW)with the acute heart failure(AHF).Methods 154 emergency patients with clinical manifestations of shortness of breath and difficulty breathing in the Guangzhou Municipal First People′s Hospital in recent 1year were collected.The whole blood cells count and NT-ProBNP were detected.The patients were divided into the AHF group(87cases),including 8cases of classⅠ,10 cases of classⅡ,36 cases of classⅢ and 33 cases of classⅣ by the NYHA classification,and the non-AHF group(67cases).Their RDW was determined by the XN-2000 automatic blood cell analyzer.Results(1)The RDW level had statistically significant difference between the AHF group and the non-AHF group(P<0.05),moreover RDW was increased with the increase of the NYHA heart function class.(2)RDW had the positive correlation with the NT-ProBNP level.Conclusion The elevated NT-ProBNP in the AHF patients is positively correlated with RDW,RDW is closely related with the severity degree of AHF,RDW combined with NT-ProBNP can be used as the simple and low-cost assisted prediction factor for the diagnosis of AHF and can be also used in clinical HF classification.更多还原