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动脉内栓塞治疗晚期膀胱癌22例临床总结
Transcatheter arterial embolization for the treatment of advanced bladder cancer: clinical analysis of 22 cases
【摘要】 目的探讨动脉内栓塞(TAE)治疗晚期膀胱癌的临床疗效。方法回顾性分析22例行TAE治疗的晚期膀胱癌患者的临床及影像资料,总结TAE治疗晚期膀胱癌的临床疗效。结果本组22例患者均成功行TAE治疗,手术成功率100%。22例患者中,术前与术后1个月腹痛评分分别为4.73±1.91和2.45±1.29(P<0.01),ECOG体能评分分别为3.14±0.47和2.68±0.56(P<0.05),血红蛋白分别为(61.4±11.8)和(79.3±14.5)g/L(P<0.01)。7例存在尿路梗阻患者中,5例尿路梗阻消失,2例梗阻症状减轻,但仍有排尿不畅。随访(7.1±3.0)(1.5~24)个月,半年生存率为54.5%(12/22)。无严重并发症发生。结论 TAE不但有效改善因肿瘤导致的血尿和尿路梗阻症状,而且还可以有效控制肿瘤生长、改善患者生活质量、延长生存期。
【Abstract】 Objective To investigate the therapeutic efficacy of transcatheter arterial embolization(TAE) in treating advanced bladder cancer. Methods A total of 22 patients with advanced bladder cancer were included in this study. The clinical data and the imaging materials were retrospectively analyzed. The clinical efficacy of TAE in treating advanced bladder cancer was evaluated. Results TAE was successfully accomplished in all the 22 patients. The preoperative and the postoperative abdominal pain scores were 4.73±1.91 and 2.45±1.29 respectively, the difference was statistically significant(P<0.01); the preoperative and the postoperative ECOG scores were 3.14±0.47 and 2.68±0.56 respectively(P<0.05); the preoperative and the postoperative hemoglobin levels were(61.4±11.8) g/L and(79.3±14.5) g/L respectively(P<0.01). Of 7patients with urinary tract obstruction, after the treatment the obstruction disappeared in 5 and was improved in 2, although the urination was still not smooth. All patients were followed up for(7.1±3.0) months. The 6-month survival rate was 54.5%(12/22). No serious complications occurred in all patients. Conclusion TAE can not only effectively improve the hematuria and urinary tract obstruction symptoms caused by bladder cancer, but also effectively control the tumor growth, improve the quality of life and prolong the survival time as well.
- 【文献出处】 介入放射学杂志 ,Journal of Interventional Radiology , 编辑部邮箱 ,2015年04期
- 【分类号】R737.14
- 【被引频次】14
- 【下载频次】109