【摘要】 目的探讨经阴道彩色多普勒超声(color doppler ultrasound,CDU)在评价自然周期供精人工授精(artificial insemination by donor,AID)结局中的价值。方法选择2011年9月至2014年3月广东省计划生育专科医院生殖中心采用CDU检查的608例行自然周期AID患者资料,按临床妊娠与否分为妊娠组(159例)和未妊娠组(449例),比较两组患者子宫内膜厚度、分型、子宫动脉血流参数、子宫内膜及内膜下血流等指标,分析不同指标与AID临床妊娠率的关系。结果两组患者的子宫内膜厚度、子宫动脉阻力指数和搏动指数比较差异均无统计学意义(P>0.05);内膜分型A型者妊娠率30.13%(91/302),高于B型者23.33%(63/210)、C型者13.89%(5/36),(P<0.05);子宫内膜及内膜下有血流者妊娠率31.58%(102/323),高于内膜及内膜下均无血流者2.44%(1/41),(P<0.05)。同一种内膜分型下,不同血流的临床妊娠率比较差异均有统计学意义(P<0.05)。结论经阴道CDU监测子宫内膜类型及子宫内膜及内膜下血流对评估子宫内膜容受性、预测临床结局有重要意义,对内膜及内膜下血流的预测价值更高。更多还原

【Abstract】 Objective To investigate the value of transvaginal color doppler ultrasound( CDU) in evaluating outcomes of natural cycles artificial insemination by donor( AID). Methods Clinical data of 608 cases underwent natural cycles AID detected by CDU in the department of reproductive center of Guangdong Family Planning Special Hospital from Sept. 2011 to Mar. 2014 were selected. All cases were divided into the conception group( n = 159) and non- conception group( n = 449). The endometrial thickness,patterns,the parameters of the uterine and endometrium blood flow were compared between two groups. The relationship between different indicators and clinical pregnancy rate of AID were analyzed. Results There were no significant differences in the endometrial thickness,uterine artery resistance index and pulsatility index between two groups( P > 0. 05). The pregnancy rate of patients with type A endometrium [30. 13%( 91 /302) ]was significantly higher than that of type B[23. 33 %( 63 /210) ]type C[13. 89%( 5 /36) ]( P < 0. 05). The pregnancy rate of patients with blood flow in endometrium and under endometrium [31. 58%( 102 /323) ] was significantly higher than that of patients without blood flow in endometrium and under endometrium [2. 44%( 1 /41) ]( P < 0. 05).Among the same type of endometrium with different blood flow,the difference of pregnancy rate had statistical significance( P <0. 05). Conclusion Endometrial patterns and blood flow under endometrium detected by transvaginal CDU have significance in evaluating endometrial receptivity and predicting the clinical outcomes. The blood flow in endometrium and under endometrium has higher predictive value.更多还原